Research Assistant Professor, Hematology & Oncology

Overview

The Cancer Center at the University of Virginia seeks a Research Assistant Professor to work in the laboratory of Thomas Loughran Jr., MD (https://www.loughranlab.com/). The incumbent joins an interactive group of motivated scientists to study the pathogenesis and treatment of hematologic malignancies with a focus on large granular lymphocyte (LGL) leukemia and acute myeloid leukemia (AML). The candidate will join a highly collaborative research team to investigate the pathogenic mechanisms in LGL leukemia including somatic mutations; epigenetic, biochemical, and signaling alterations; and immunologic events such as antigenic drivers of cytotoxic T-cell responses. Therapeutic development efforts will include target identification, validation, and rationale; in vitro testing and mechanistic studies in cell lines and primary patient samples; and in vivo efficacy trials in preclinical models to support the translational development of approved and experimental therapeutics alone and in combination regimens.

The position will require administrative and managerial duties, including but not limited to, implementing laboratory biosafety and chemical safety guidelines, completing regulatory filings for animal usage and human subjects research, managing and guiding research projects in the lab, and coordinating collaborative research projects with investigators within UVA and at other institutions.

The position will also contribute to the writing of manuscripts and grant applications, therefore demonstrated experience and success in these areas is required.  ­­­Successful candidates must have effective oral and written communication skills as evidenced by a solid track record of scientific manuscripts and poster presentations.

Description:
Candidate must have a PhD degree in Molecular Medicine, Molecular Biology, Cell Biology, or related.

A minimum of five years of research experience to include each of the following: cell biology, molecular biology, cell and cytokine/chemokine signaling, immunology, flow cytometry, T-cell and NK cell biology, drug screening, culture and genetic manipulation of primary human material and cell lines, as well as pre-clinical in vitro and in vivo experimental therapeutic development is preferred.

The position will provide instruction, training, and mentoring to undergraduate and graduate students and technicians, therefore a minimum of one year of experience in a teaching capacity (including teaching assistant or tutor) is preferred. Experience acquired as an undergraduate or graduate student is acceptable.